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Glimepiride 1 mg + Metformin 500 mg (SR) Tablets
Anti-Diabetic
Type 2 Diabetes Mellitus — initial or insufficient monotherapy
HbA1c lowering effect was Statistically Superior in the G/M FDC group compared with the Met UP Group
The response rate, defined as the ratio of patients achieving each HbA1c, 7% and FPG.140 mg/dl, was significantly higher in the G/M FDC Group
The titration period was shorter in the G/M FDC Group than the Met Up Group
Early combination therapy with glimepiride and Metformin could provide the benigit of earlier glucose control, avoiding nagative glycemic memory ralated to micro and macro- vascular complication.
• Glimepiride stimulates insulin secretion from pancreatic beta cells
• Metformin reduces hepatic glucose output and enhances insulin sensitivity
• Step-up dosing flexibility: M1 (1 mg Glimepiride) or M2 (2 mg Glimepiride)
• Complementary dual mechanism: targets both insulin resistance and secretion