A power pill for unseen pain
Nortriptyline
Inhibits the reuptake of serotonin and norepinephrine by the presynaptic neuronal membrane, thereby increasing the concentration of those neurotransmitters in the synapse. Additionally, nortriptyline inhibits the activity of histamine, 5- hydroxytryptamine, and acetylcholine, thus helping patients battling neuropathic pain / distress.
Pregabalin
Inhibits the reuptake of serotonin and norepinephrine by the presynaptic neuronal membrane, thereby increasing the concentration of those neurotransmitters in the synapse. Additionally, nortriptyline inhibits the activity of histamine, 5- hydroxytryptamine, and acetylcholine, thus helping patients battling neuropathic pain/distress.
Neuropathic pain is relieved more effectively by combination treatment with the anticonvulsant Gabapentin and the antidepressant Nortriptyline than by treatment with either drug alone, a study published online in the lancet has shown.
Methylcobalamin
Protects the myelin sheath and thus nerves; Improves nerve conduction & prevents peripheral neuropathy.