Rifaximin is a rifamycin derivative antibiotic that works by inhibiting bacterial RNA synthesis. It has poor absorption from the gastrointestinal tract, which means it works mainly locally in the intestine with minimal systemic side effects.
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Traveler’s Diarrhea (caused by non-invasive strains of E. coli)
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Irritable Bowel Syndrome with Diarrhea (IBS-D)
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Hepatic Encephalopathy (for reducing risk of recurrence by decreasing ammonia-producing gut bacteria)
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Small Intestinal Bacterial Overgrowth (SIBO) – off-label use
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It's important to follow your doctor's directions when taking medicine